2022
Tracking raw material flow through a continuous direct compression line Part I of II: Residence time distribution modeling and sensitivity analysis enabling increased process yield Authors: M. Peterwitz, J. Jodwirschat, R. Loll, G. Schembecker | research paper | DDIC | |
Tracking raw material flow through a continuous direct compression line. Part II of II: Predicting dynamic changes in quality attributes of tablets due to disturbances in raw material properties using an independent residence time distribution model Authors: M. Peterwitz, S. Buchgeister, R. Meier, G. Schembecker | research paper | DDIC | |
Factors Influencing the Crystallization-Onset Time of Metastable ASDs Authors: F. Wolbert, I.-K Fahrig, T. Gottschalk, C. Luebbert, M. Thommes and G. Sadowski | research paper | DDIC | |
Influence of process temperature and residence time on the manufacturing of amorphous solid dispersions in hot melt extrusion Authors: T. Gottschalk, B. Grönniger ,E. Ludwig, F. Wolbert, T. Feuerbach, G. Sadowski and M. Thommes | research paper | DDIC | |
Challenges in tracing material flow passing a loss-in-weight feeder in continuous manufacturing processes Authors: M. Peterwitz, S. Gerling, G. Schembecker | research paper | DDIC | |
Simplified choice of suitable excipients within biologics formulation design using protein-protein interaction- and water activity-maps Authors: T. Stolzke, C. Brandenbusch | research paper | DDIC | |
Development of sustained-release drug-loaded intravesical inserts via semi-solid micro-extrusion 3D-printing for bladder targeting Authors: J. Rahman-Yildir, B. Fischera, J. Breitkreutz | research paper | DDIC | |
Comparative dissolution studies of 3D-printed inserts in a novel biopharmaceutical bladder model Authors: J. Rahman-Yildir, R. Wiedey , J. Breitkreutz | research paper | DDIC | |
Predicting Throughput and Melt Temperature in Pharmaceutical Hot Melt Extrusion Authors: T. Gottschalk, C. Özbay, T. Feuerbach, M. Thommes | research paper | DDIC | |
Hydroxylpropyl-β-cyclodextrin as Potential Excipient to Prevent Stress-Induced Aggregation in Liquid Protein Formulations Authors: T. Stolzke, F. Krieg, T. Peng, H. Zhang, O. Häusler, C. Brandenbusch | research paper | DDIC | |
The Shelf Life of ASDs: 1. Measuring the Crystallization Kinetics at Humid Conditions Authors: F. Wolbert, K. Nikoleit, M. Steinbrink, C. Luebbert, G. Sadowski | research paper | DDIC | |
Nano-Dry-Melting: A Novel Technology for Manufacturing of Pharmaceutical Amorphous Solid Dispersions Authors: Hermeling M, Nueboldt C, Heumann R, Hoheisel W, Breitkreutz J. | research paper | ||
Reduction of Submicron Particle Agglomeration via Melt Foaming in Solid Crystalline Suspension Authors:P. da Igreja, D. Klump, J. Bartsch, M. Thommes | research paper |